Specializing in DNA damage response, autophagy, and chemoresistance. Passionate about translating fundamental research into therapeutic applications.
Hello! I'm a passionate and curious researcher with a PhD focused on understanding cellular responses to stress, particularly the intricate mechanisms of the DNA damage response and autophagy pathways. My doctoral studies specifically highlighted how proteins like MDC1 interact with autophagy-related components to play a non-canonical role in DNA repair.
My fascination extends to the broader interplay between various cellular pathways and their intricate regulation. I'm especially intrigued by how fundamental mechanisms, such as DNA repair, contribute to cellular homeostasis and how their dysregulation can lead to significant pathologies, including cancer. This interest drives my commitment to exploring these complex processes and their implications for human health.
I bring extensive hands-on experience in a variety of advanced laboratory techniques, including western blotting, immunocytochemistry, co-immunoprecipitation studies, flow cytometry, apoptosis detection, and diverse cell-based assays. I am dedicated to scientific discovery, thrive in collaborative environments, and am always eager to apply and upgrade my skills to challenging research questions aimed at making a tangible impact.
Investigating MDC1 and its role in cellular stress responses
Cross-talk between DDR and autophagy pathways
Programmable nucleases for molecular diagnostics
Molecular targets for therapeutic intervention
Recent research contributions in molecular biology and cancer research
K Pandya, D Jagani, N Singh
Molecular Biotechnology 66 (8), 1739-1753 (2024)
K Pandya, N Singh
Molecular Diversity 27 (6), 2789-2802 (2023)
S Vyas, K Pandya, N Singh, R Mishra
Journal of Molecular Structure, 142732 (2025)
N Singh, K Pandya
Journal of Biological Chemistry 301 (5) (2025)
KA Pandya, N Singh
Cancer Research 85 (8_Supplement_1), 4198-4198 (2025)
S Rathore, R Bhatt, S Joshi, K Pandya, N Singh
CRISPR-Cas System in Translational Biotechnology, 265-280 (2024)
Institute of Advanced Research
Project: Investigate The Interplay Between MDC1 And Beclin-1 In Oxidative Stress And Drug Induced DNA Damage
Gujarat Biotechnology Research Centre
Project: Global Challenge Research Fund - One Health Poultry Hub
Amneal Pharmaceuticals
Gained hands-on experience in sterility testing and microbial contamination analysis in drug manufacturing processes.
Institute of Advanced Research, Gandhinagar
Dissertation on DDR-Autophagy cross-talk in cellular stress responses
Nirma University
Dissertation: Identification and cloning of novel Rab9 homologue in Entamoeba histolytica
St. Xavier's College, Ahmedabad
Foundation in biochemistry, molecular biology, and analytical techniques
I'm actively seeking opportunities in research and development. Let's connect to discuss potential collaborations or positions.